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Ergotamine-induced lower extremity arterial vasospasm presenting as acute limb ischemia.
MedLine Citation:
PMID:  19821256     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Ergotamine-induced limb ischemia is rare and usually results from an accidental overdose. Several agents, including erythromycin and tetracycline, raise serum ergotamine levels and augment its effect. We present a case of acute lower limb ischemia with characteristic angiography findings of diffuse arterial spasm resulting from use of ergotamine and an erythromycin derivative, clarithromycin. The history of the patient and classic features seen on angiography helped us establish the diagnosis. The patient was successfully treated with low molecular heparin and epidural infusion of bupivacain. Since ergot vasospasm is a self limited and medically treatable condition, interventional radiologists must be aware of ergotamine-induced acute limb ischemia to avoid any unnecessary interventional procedures, unless necrosis and gangrene are imminent.
Authors:
Senay Demir; Sule Akin; Fahri Tercan; Anis Aribo?an; Levent O?uzkurt
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Publication Detail:
Type:  Journal Article     Date:  2009-10-09
Journal Detail:
Title:  Diagnostic and interventional radiology (Ankara, Turkey)     Volume:  16     ISSN:  1305-3612     ISO Abbreviation:  Diagn Interv Radiol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101241152     Medline TA:  Diagn Interv Radiol     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  165-7     Citation Subset:  IM    
Affiliation:
Department of Radiology, Ba?kent University Adana Medical and Research Center, Adana, Turkey. drsenaydemir@hotmail.com
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