Document Detail

Erdheim-Chester Disease With Prominent Pericardial Effusion: Cytologic Findings and Review of the Literature.
MedLine Citation:
PMID:  23447119     Owner:  NLM     Status:  Publisher    
Erdheim-Chester disease (ECD) is a rare, non-Langerhans form of histiocytosis of unknown origin with distinct clinicopathologic and radiographic features. Reports detailing the cytology of ECD are rare. We describe a case of ECD with pericardial effusion. Cytologic examination revealed a hypercellular specimen composed of clusters and singly dispersed foamy macrophages with round nuclei and inconspicuous nucleoli, admixed with lymphocytes, eosinophils, and Touton-type multinucleated giant cells. Immunostains for CD68 were strongly positive in the foamy macrophages while S100 and CD1a were negative. The presence of foamy histiocytes, multinucleated giant cells, lymphocytes and eosinophils are also features of other systemic histiocytic disorders, including Langerhans cell histiocytosis (LCH), Rosai-Dorfman disease (RDD) and sarcoidosis. To the best of out knowledge, this is the first report describing the cytological features of ECD in a pericardial effusion. Diagn. Cytopathol. 2013;. © 2013 Wiley Periodicals, Inc.
Borislav A Alexiev; Paul N Staats
Related Documents :
15076929 - Tuberculous epididymo-orchitis presenting within the setting of a sexually transmitted ...
11022389 - Typhoid and paratyphoid fever in south-eastern sydney, 1992-1997.
2316769 - Evaluation of active versus passive aids surveillance in oregon.
11127239 - Investigation of the spread of human visceral leishmaniasis in central tunisia.
11745839 - Using active medical record review and capture-recapture methods to investigate the pre...
6476199 - The distribution of visceral leishmaniasis in ethiopia.
19321399 - Obstructive colitis proximal to obstructive colorectal carcinoma.
25386319 - Zosteriform metastases from colon carcinoma: an unusual pattern.
19859019 - Myocardial abscess and bacteremia complicating mycobacterium fortuitum pacemaker infect...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-28
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  -     ISSN:  1097-0339     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Wiley Periodicals, Inc.
Department of Pathology, University of Maryland Medical Center, Baltimore, Maryland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Intramedullary schwannomas: long-term outcomes of ten operated cases.
Next Document:  Enantioselective Total Synthesis of (+)-Ophiobolin?A.