Document Detail

Eradication of intra-amniotic Streptococcus mutans in a woman with a short cervix.
MedLine Citation:
PMID:  17140507     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Microbial invasion of the amniotic cavity (MIAC) remains an important pathogenetic factor in preterm births. Although most MIACs seem to originate in vaginal microflora, other reservoirs such as the oral microflora have been suggested. CASE: We report a case of successful eradication of Streptococcus mutans (a bacterium generally found in dental plaque) from the amniotic cavity, using ampicillin, gentamycin, and azythromycin in a woman who presented with threatened preterm labour and a short cervix at 25 weeks' gestation. She delivered at 34 weeks' gestation and was treated for tooth decay 12 weeks after delivery. CONCLUSION: Intra-amniotic infection should be suspected in the presence of a short cervix during the second trimester. Appropriate parenteral antibiotics can eradicate intra-amniotic infection and potentially prolong pregnancy.
Anne Maude Morency; Fabien Rallu; Céline Laferrière; Emmanuel Bujoldg
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC     Volume:  28     ISSN:  1701-2163     ISO Abbreviation:  J Obstet Gynaecol Can     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-07-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101126664     Medline TA:  J Obstet Gynaecol Can     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  898-902     Citation Subset:  IM    
Department of Microbiology, Centre Hospitalier Universitaire-Hôpital Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
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MeSH Terms
Amniotic Fluid / microbiology*
Anti-Bacterial Agents / therapeutic use*
Cervix Uteri / anatomy & histology
Pregnancy Complications, Infectious / drug therapy*
Premature Birth / drug therapy,  prevention & control
Streptococcal Infections / drug therapy*
Streptococcus mutans*
Treatment Outcome
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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