Document Detail

Eradication of infectious diseases: its concept, then and now.
MedLine Citation:
PMID:  14985628     Owner:  NLM     Status:  MEDLINE    
The concept of disease eradication emerged as recently as the mid-20th century. The successful eradication of smallpox resulted in the concept of the extinction of the causative agent in man as well as in the environment, leading to the cessation of all control measures including vaccination. Subsequently, world resources have been invested in global polio eradication and measles eradication in the Western Hemisphere. The former is apparently now at the "end game", the latter, after successful campaign in the Americas, aims at program development worldwide. However, both endeavors are being challenged by delays in schedules, unexpected technical problems, lack of global coordination, and ever-increasing political unrest. It is proposed that disease eradication be redefined as the extinction of the pathogen in man, not in nature, making for a more flexible approach in the post-eradication period. Smallpox eradication was a rare event. That concept is unrealistic in today's world.
Isao Arita; John Wickett; Miyuki Nakane
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Japanese journal of infectious diseases     Volume:  57     ISSN:  1344-6304     ISO Abbreviation:  Jpn. J. Infect. Dis.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-26     Completed Date:  2004-06-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100893704     Medline TA:  Jpn J Infect Dis     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
Agency for Cooperation in International Health, Kumamoto 862-0901, Japan.
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MeSH Terms
Communicable Disease Control* / methods
Communicable Diseases* / epidemiology,  immunology
Immunization Programs
Measles / prevention & control
Measles Vaccine
Poliomyelitis / prevention & control
Smallpox / prevention & control
Smallpox Vaccine
World Health*
Reg. No./Substance:
0/Measles Vaccine; 0/Smallpox Vaccine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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