Document Detail

Eradication of Helicobacter pylori in patients with non-ulcer dyspepsia.
MedLine Citation:
PMID:  8102009     Owner:  NLM     Status:  MEDLINE    
Non-ulcer dyspepsia is an unsatisfactory term, as it describes a spectrum of conditions. The term is used for patients who have a normal upper endoscopy, macroscopically, but who have persistent upper gastrointestinal symptoms. Patients with non-ulcer dyspepsia respond to a wide variety of treatments, and there is a strong placebo response. Fifty per cent of these patients are shown to have Helicobacter pylori present if biopsy specimens are taken at endoscopy. Previous studies suggest that H. pylori eradication improves patients' symptoms. In a study from our unit we have shown that, in the short term, patients' symptoms improved with treatment, independent of H. pylori status. However, at 1-year follow-up, prolonged improvement of symptoms was observed only in patients in whom the organism had been eradicated.
C O'Moráin; J Gilvarry
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Scandinavian journal of gastroenterology. Supplement     Volume:  196     ISSN:  0085-5928     ISO Abbreviation:  Scand. J. Gastroenterol. Suppl.     Publication Date:  1993  
Date Detail:
Created Date:  1993-08-31     Completed Date:  1993-08-31     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0437034     Medline TA:  Scand J Gastroenterol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  30-3     Citation Subset:  IM    
Dept. of Gastroenterology, Meath/Adelaide Hospitals, Trinity College, Dublin, Ireland.
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MeSH Terms
Dyspepsia / drug therapy,  microbiology*
Helicobacter pylori / drug effects*
Histamine H2 Antagonists / pharmacology
Reg. No./Substance:
0/Histamine H2 Antagonists

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