Document Detail


Equine ehrlichial colitis: effect of oxytetracycline treatment during the incubation period of Ehrlichia risticii infection in ponies.
MedLine Citation:
PMID:  3356569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Equine ehrlichial colitis was experimentally induced in 18 ponies, using Ehrlichia risticii-infected blood. Four ponies (group 1) were treated with oxytetracycline (6.6 mg/kg of body weight, IV, q 12 h), beginning 14 hours before inoculation and continuing for 5 days after inoculation. Four additional ponies (group 2) were treated similarly for 10 days after inoculation. The remaining 10 ponies were used as nontreated, infected controls. Clinical disease was delayed in 3 group-1 ponies and in 4 group-2 ponies. Protective immunity developed in the remaining pony that did not develop clinical disease and in 1 group-1 pony and 2 group-2 ponies that developed mild, transient clinical signs.
Authors:
J E Palmer; R H Whitlock; C E Benson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  192     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-05-16     Completed Date:  1988-05-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  343-5     Citation Subset:  IM    
Affiliation:
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
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MeSH Terms
Descriptor/Qualifier:
Animals
Colitis / drug therapy,  microbiology,  veterinary*
Ehrlichia / growth & development
Horse Diseases / drug therapy*,  microbiology
Horses
Oxytetracycline / therapeutic use*
Rickettsiaceae Infections / drug therapy,  veterinary*
Chemical
Reg. No./Substance:
79-57-2/Oxytetracycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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