Document Detail

Epstein-Barr virus infection in pregnancy--a prospective controlled study.
MedLine Citation:
PMID:  18534816     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Epstein-Barr virus (EBV) is one of the most common human viruses. To date, there is limited information regarding the influence of maternal EBV infection on pregnancy outcome. OBJECTIVE: Our aim was to examine the fetal safety of EBV infection in pregnancy. STUDY DESIGN: We prospectively evaluated the rate of major anomalies and pregnancy outcome of women with serologic evidence of primary, recurrent or undefined infection (27, 56, and 43 women, respectively) compared to 1434 women who called the Israeli TIS for non-teratogenic exposure. RESULTS: Women's characteristics and pregnancy outcome were comparable between the EBV exposed and control groups. Similarly, the gestational age at delivery and birth weight were not significantly different. The rate of major congenital anomalies did not significantly differ between the EBV exposed compared to the control group. CONCLUSION: This study suggests that EBV infection during pregnancy does not represent a major teratogenic risk to the fetus.
Meytal Avgil; Orna Diav-Citrin; Svetlana Shechtman; Judy Arnon; Rebecka Wajnberg; Asher Ornoy
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Publication Detail:
Type:  Journal Article     Date:  2008-04-30
Journal Detail:
Title:  Reproductive toxicology (Elmsford, N.Y.)     Volume:  25     ISSN:  0890-6238     ISO Abbreviation:  Reprod. Toxicol.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-22     Completed Date:  2009-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8803591     Medline TA:  Reprod Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  468-71     Citation Subset:  IM    
The Israeli Teratogen Information Service, Israel Ministry of Health Jerusalem, Israel.
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MeSH Terms
Epstein-Barr Virus Infections / epidemiology*
Israel / epidemiology
Pregnancy Outcome / epidemiology*
Prospective Studies

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