Document Detail

Epoprostenol treatment for idiopathic pulmonary arterial hypertension in pregnancy.
MedLine Citation:
PMID:  20802509     Owner:  NLM     Status:  MEDLINE    
Idiopathic pulmonary arterial hypertension is a rare condition associated with significant maternal mortality. We report the management of a 37-year-old multigravida with severe disease using epoprostenol, a multidisciplinary approach, and a planned delivery. Although the patient survived the pregnancy, her pulmonary function significantly worsened. Epoprostenol, a pulmonary vasodilator, should be considered when indicated during pregnancy. Neither fetal nor neonatal harm was identified.
M J Garabedian; W F Hansen; E A Gianferrari; K Y Lain; R Y Fragneto; C L Campbell; D C Booth
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  30     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-30     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  628-31     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Kentucky, Lexington, KY, USA.
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MeSH Terms
Antihypertensive Agents / therapeutic use*
Cesarean Section, Repeat
Epoprostenol / therapeutic use*
Hypertension, Pulmonary / drug therapy*
Patient Care Team
Pregnancy Complications, Cardiovascular / drug therapy*
Reg. No./Substance:
0/Antihypertensive Agents; 35121-78-9/Epoprostenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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