| Eplerenone. Pharmacia. | |
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MedLine Citation:
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PMID: 12744223 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pharmacia Corp (formerly GD Searle & Co) is developing eplerenone, an aldosterone receptor antagonist, as a potential treatment for congestive heart failure and systemic hypertension. The compound has been registered for hypertension and Pharmacia plans to submit a supplemental NDA for congestive heart failure in the first half of 2003 based on positive results from a phase III clinical trial. |
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Authors:
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Danny Liew; Jennifer Martin; Henry Krum |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in investigational drugs (London, England : 2000) Volume: 4 ISSN: 1472-4472 ISO Abbreviation: Curr Opin Investig Drugs Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-05-08 Completed Date: 2003-07-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100965718 Medline TA: Curr Opin Investig Drugs Country: England |
Other Details:
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Languages: eng Pagination: 316-22 Citation Subset: IM |
Affiliation:
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National Health and Medical Research Council, Department of Epidemiology, Monash University Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria 3004, Australia. danny.liew@med.monash.edu.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aldosterone Antagonists*
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adverse effects,
pharmacology,
therapeutic use Animals Clinical Trials as Topic Humans Hypertension / drug therapy, metabolism Receptors, Aldosterone / antagonists & inhibitors Spironolactone* / adverse effects, analogs & derivatives*, pharmacology, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Aldosterone Antagonists; 0/Receptors, Aldosterone; 0/eplerenone; 52-01-7/Spironolactone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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