Document Detail


Epithelial tumours of the adult kidney.
MedLine Citation:
PMID:  10335938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The epithelial tumours of the adult kidney, in particular renal cell carcinoma (RCC), are a variety of neoplasms that can be classified by morphology and genotype. Although most are well characterised, typical and less typical tumour variants are recognised. There is evidence to indicate that stage is one of the most important prognostic factors, irrespective of tumour subtype. However, the appropriate handling of nephrectomy specimens is essential for accurate evaluation of diagnostic and prognostic factors in RCC. The problem of how to achieve more objective nuclear grading is still unresolved. The use of diagnostic decision support systems offers the possibility of a flexible approach to this problem, while still utilising morphological criteria. The histopathological analysis remains important, but new techniques of molecular and cell biology will be providing new tools of extraordinary power to sharpen the diagnosis and give it a biological interpretation.
Authors:
R Montironi; G Mikuz; F Algaba; A Lopez-Beltran; P W Hamilton; C Parkinson
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Publication Detail:
Type:  Congresses; Review    
Journal Detail:
Title:  Virchows Archiv : an international journal of pathology     Volume:  434     ISSN:  0945-6317     ISO Abbreviation:  Virchows Arch.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-06-03     Completed Date:  1999-06-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9423843     Medline TA:  Virchows Arch     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  281-90     Citation Subset:  IM    
Affiliation:
Institute of Pathological Anatomy, University of Ancona School of Medicine, Regional Hospital, Torrette di Ancona, Italy. r.montironi@poscsi.unian.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Carcinoma, Renal Cell / classification,  pathology*
Humans
Kidney Neoplasms / classification,  pathology*
Neoplasm Staging

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