Document Detail

Epithelial inclusions in association with mucin ball development in high-oxygen permeability hydrogel lenses.
MedLine Citation:
PMID:  10701804     Owner:  NLM     Status:  MEDLINE    
Debris trapped behind contact lenses may be associated with adverse reactions in extended wear. Although streaks and clumps of cellular material have been reported after overnight wear of conventional materials, recent experience with several high-oxygen permeability (Dk), silicone-containing hydrogel lenses indicates that certain participants are prone to the development of a unique back surface debris. This debris forms as spherical, translucent entities and results in depressions within the ocular surface after lens removal. Little information is known about these spherical bodies, particularly with respect to their composition and development. In this report, we provide photographic evidence of this debris (sometimes termed "mucin balls" or "lipid plugs"), discuss its differential diagnosis and describe a case in which material seems to be embedded in the epithelium as a direct consequence of their presence.
N Pritchard; L Jones; K Dumbleton; D Fonn
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Optometry and vision science : official publication of the American Academy of Optometry     Volume:  77     ISSN:  1040-5488     ISO Abbreviation:  Optom Vis Sci     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-03-29     Completed Date:  2000-03-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8904931     Medline TA:  Optom Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  68-72     Citation Subset:  IM    
Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada.
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MeSH Terms
Contact Lenses, Extended-Wear / adverse effects*
Corneal Diseases / diagnosis,  etiology*,  metabolism
Diagnosis, Differential
Epithelium, Corneal / metabolism,  pathology*
Inclusion Bodies / pathology*
Mucins / metabolism*
Oxygen / metabolism*
Reg. No./Substance:
0/Mucins; 25852-47-5/Hydrogel; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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