Document Detail

Epithelial healing and ocular discomfort after photorefractive keratectomy in children.
MedLine Citation:
PMID:  12663009     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To document the rate of healing of the corneal epithelial defect created by photorefractive keratectomy (PRK) and the degree of discomfort experienced by children treated with PRK. SETTING: Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA. METHODS: Ten patients between 3 and 10 years of age were treated with PRK for severe anisometropia. All had anisometropic amblyopia refractory to conventional therapy with glasses or contact lenses and occlusion therapy. The size of the corneal epithelial defect was documented daily until the defect healed completely. Postoperative discomfort was documented daily using a pain-assessment scale until the epithelial defect healed completely. RESULTS: Two children were treated with PRK for hyperopic anisometropia; the rest were treated for myopic anisometropia. Cumulatively, the corneal epithelium had healed completely by day 3 in 6 patients (60%), by day 4 in 9 patients (90%), and by day 5 in all patients. The mean healing time was 3.5 days. Patients experienced mild discomfort on the day of surgery and on the first postoperative day. They had minimal pain on day 2. After day 2, no patient reported pain or other discomfort. CONCLUSIONS: The corneal epithelial defect created by PRK healed promptly and was associated with minimal postoperative discomfort in children treated with the protocol described.
Evelyn A Paysse; M Bowes Hamill; Douglas D Koch; Mohamed A W Hussein; Kathryn M Brady McCreery; David K Coats
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cataract and refractive surgery     Volume:  29     ISSN:  0886-3350     ISO Abbreviation:  J Cataract Refract Surg     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-28     Completed Date:  2003-05-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8604171     Medline TA:  J Cataract Refract Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  478-81     Citation Subset:  IM    
Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas 77030, USA.
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MeSH Terms
Anisometropia / surgery*
Child, Preschool
Epithelial Cells / physiology
Epithelium, Corneal / physiology*
Hyperopia / surgery
Lasers, Excimer
Myopia / surgery
Pain Measurement
Pain, Postoperative / physiopathology*
Photorefractive Keratectomy / methods*
Time Factors
Visual Acuity
Wound Healing*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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