| Epithelial-dendritic cell interactions in allergic disorders. | |
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MedLine Citation:
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PMID: 21106358 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial to the maintenance of immune homeostasis. Dendritic cells are uniquely potent inducers of immune responses and it is increasingly clear that epithelium has the capacity to modulate the functional activity of dendritic cells, and vice versa, through production of a diverse array of mediators. Bidirectional interactions between epithelial cells and dendritic cell networks can thus impact upon the development and progression of immunity/tolerance in respiratory tissues. In this brief review we highlight the most recent advances in understanding how airway epithelial/dendritic cell interactions contribute to allergic disorders. |
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Authors:
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Deborah H Strickland; John W Upham; Patrick G Holt |
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Publication Detail:
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Type: Journal Article Date: 2010-11-23 |
Journal Detail:
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Title: Current opinion in immunology Volume: 22 ISSN: 1879-0372 ISO Abbreviation: Curr. Opin. Immunol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8900118 Medline TA: Curr Opin Immunol Country: England |
Other Details:
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Languages: eng Pagination: 789-94 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Telethon Institute for Child Health Research, and Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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