Document Detail


Epistaxis in hereditary haemorrhagic telangiectasia.
MedLine Citation:
PMID:  8938889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hereditary haemorrhagic telangiectasia (HHT) is characterized by easily bleeding telangiectases of the skin and mucosa. Epistaxis is the most common symptom of HHT. Larger arteriovenous malformations (AVM) occur in the lungs (in up to 33% of the patients), brain (in up to 11% of patients), and liver. These may cause severe complications which can be prevented by early therapy. To gain insight in the characteristics of epistaxis in HHT, 171 persons were investigated, who either had HHT or participated in a screening programme for relatives of HHT patients. Of these, 58 persons had HHT. Epistaxis without signs of HHT was present in 12 persons, whereas 10% of HHT patients did not have epistaxis. Seventeen HHT patients with epistaxis had visited an otorhinolaryngologist before, without a correct diagnosis of HHT being made. Telangiectases were most common on lips, tongue, the nasal septum, and the turbinates. In view of the prevalence of visceral AVM and the associated complications, HHT patients presenting to an otorhinolaryngologist should be encouraged to engage in a screening programme for these AVM.
Authors:
T Haitjema; W Balder; F J Disch; C J Westermann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Rhinology     Volume:  34     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-02-26     Completed Date:  1997-02-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  176-8     Citation Subset:  IM    
Affiliation:
Department of Pulmonology, Sint Antonius Hospital, Nieuwegein, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adult
Epistaxis / epidemiology,  etiology*
Female
Humans
Incidence
Male
Mass Screening
Recurrence
Telangiectasia, Hereditary Hemorrhagic / complications*,  prevention & control

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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