Document Detail

Episodic nocturnal wanderings in non-epileptic young patients.
MedLine Citation:
PMID:  3381056     Owner:  NLM     Status:  MEDLINE    
Twelve patients, aged 19 to 29 years, presented with episodic nocturnal wanderings characterized by stereotyped frequent attacks of screaming, ambulation, and complex automatisms during sleep. The attacks ranged in frequency from two or three per year to several per night and were often associated with semi-purposeful violent and even life-threatening behavior. None of the patients had a history of seizures; three had a history of prior parasomnias and four had family members with a history of parasomnia. Polysomnographic and daytime electroencephalographic (EEG) investigations showed potentially epileptiform activity in four patients. Recorded episodes were not accompanied by ictal EEG activity. Anticonvulsant medication reduced or eliminated the attacks in all of the nine treated patients. The pathophysiology of the disorder is uncertain.
R A Maselli; R S Rosenberg; J P Spire
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Sleep     Volume:  11     ISSN:  0161-8105     ISO Abbreviation:  Sleep     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-07-22     Completed Date:  1988-07-22     Revised Date:  2009-01-29    
Medline Journal Info:
Nlm Unique ID:  7809084     Medline TA:  Sleep     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  156-61     Citation Subset:  IM    
Department of Neurology, University of Chicago, Illinois.
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MeSH Terms
Brain / physiopathology*
Carbamazepine / therapeutic use
Monitoring, Physiologic
Phenobarbital / therapeutic use
Phenytoin / therapeutic use
Somnambulism / drug therapy,  physiopathology*
Reg. No./Substance:
298-46-4/Carbamazepine; 50-06-6/Phenobarbital; 57-41-0/Phenytoin
Comment In:
Sleep. 1989 Apr;12(2):186-8   [PMID:  2711095 ]

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