Document Detail


Episodic cerebellar dysfunction in a bichon frise: a canine case of episodic ataxia?
MedLine Citation:
PMID:  20536690     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A four-year-old neutered male bichon frise was presented for the evaluation of chronic, progressive yet episodic neurological dysfunction that was predominantly cerebellar in nature. Diagnostic testing including haematology, serum chemistry, magnetic resonance imaging, cerebrospinal fluid analysis and urine organic acid screening was normal. Trial therapies with phenobarbital, prednisone and acetazolamide were unsuccessful. Treatment with 4-aminopyridine led to complete resolution of the signs.
Authors:
A L Hopkins; J Clarke
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of small animal practice     Volume:  51     ISSN:  1748-5827     ISO Abbreviation:  J Small Anim Pract     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-30     Completed Date:  2010-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0165053     Medline TA:  J Small Anim Pract     Country:  England    
Other Details:
Languages:  eng     Pagination:  444-6     Citation Subset:  IM    
Affiliation:
North Florida Neurology, 280 Corporate Way, Orange Park, FL 32073, USA.
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MeSH Terms
Descriptor/Qualifier:
4-Aminopyridine / therapeutic use*
Animals
Anticonvulsants / therapeutic use*
Cerebellar Diseases / diagnosis,  drug therapy,  veterinary*
Dog Diseases / diagnosis*,  drug therapy
Dogs
Magnetic Resonance Imaging
Male
Spinocerebellar Ataxias / diagnosis,  drug therapy,  veterinary*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anticonvulsants; 504-24-5/4-Aminopyridine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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