Document Detail

Epinephrine fraction of adrenal vein blood in pheochromocytoma.
MedLine Citation:
PMID:  7148891     Owner:  NLM     Status:  MEDLINE    
Variability in the levels of epinephrine (E) and norepinephrine (NE) in adrenal vein blood is thought to preclude their usefulness in caval sampling studies for localizing abdominal pheochromocytoma. In this study we demonstrate, in three patients, that the fraction of the total catecholamine level in the adrenal effluent represented by E (E fraction) may differentiate the normal adrenal medulla from the gland containing a pheochromocytoma. This observation is additionally supported by calculations of the E fractions, from adrenal venous E and NE reported recently, in three other patients with pheochromocytoma. Our data, combined with those from the literature, yield a mean E fraction, in adrenal vein blood, of 63.8 +/- 11.4 (SD)% for seven normal adrenal medullae, and of 28.5 +/- 4.8% for five glands bearing pheochromocytoma. The use of this parameter for lateralizing adrenal pheochromocytoma is suggested if other procedures are unable to demonstrate the tumor.
V Fiorica; D C Galloway; J L Males; R P Painton; D C Kem
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  284     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:    1982 Nov-Dec
Date Detail:
Created Date:  1983-01-07     Completed Date:  1983-01-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  9-15     Citation Subset:  AIM; IM    
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MeSH Terms
Adrenal Gland Neoplasms / blood*,  diagnosis
Adrenal Glands / blood supply
Epinephrine / blood*
Middle Aged
Norepinephrine / blood
Pheochromocytoma / blood*,  diagnosis
Reg. No./Substance:
51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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