| Epileptiform discharges augmented during sleep: is it a trait with diverse clinical presentation according to age of expression? | |
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MedLine Citation:
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PMID: 19910161 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sleep has long been viewed as a negative phenomenon; however, it is now clear that it is a period of intense brain activity involving higher cortical functions. Overall, sleep affects every aspect of a child's development, particularly higher cognitive functions. The seizure threshold is often affected by changes in the level of arousal, and many interictal EEG abnormalities are activated by sleep. Epileptiform discharges augmented during sleep are described in number of epileptic syndromes characterized by infrequent clinical seizures but significant cognitive deterioration, the prototype of which is the syndrome of continuous spike-wave discharges during sleep (CSWS). In this article the conditions sharing the same EEG feature of paroxysmal epileptiform discharges augmented during sleep and their overlap will be highlighted arguing whether these disorders may be clinical presentations of same trait when expressed at different stages of brain maturity, as well as the controversies in definition and management of cases without clinical seizures. |
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Authors:
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Hanan M El Shakankiry |
Publication Detail:
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Type: Journal Article; Review Date: 2009-11-11 |
Journal Detail:
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Title: Epilepsy research Volume: 89 ISSN: 1872-6844 ISO Abbreviation: Epilepsy Res. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-29 Completed Date: 2010-06-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703089 Medline TA: Epilepsy Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 113-20 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier B.V. All rights reserved. |
Affiliation:
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Pediatric Neurology Division - Pediatric Department, King Fahd University Hospital of King Faisal University - Al Khobar, KSA, P.O. Box: 40284, Zip Code: 31952 - Al Khobar, Saudi Arabia. hshakankiry@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Brain / physiopathology* Electroencephalography Epilepsy / physiopathology* Humans Sleep / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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