Document Detail


Epileptic syndromes in childhood.
MedLine Citation:
PMID:  3066614     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Epileptic syndromes are clusters of signs and symptoms regularly occurring together. These may include type of seizure(s), time and circumstances of occurrence, and neurological and EEG findings. Some syndromes have common signs and a predictable course (e.g., benign rolandic epilepsy). Others, such as absence seizures, are less specific and may include several subgroups with different outcomes and different associated features. Still others are rather loose collections of a few common characteristics irregularly linked together. Widely accepted syndromes in childhood include the West syndrome and Lennox-Gastaut syndromes, several myoclonic syndromes, febrile seizures of infancy, absence epilepsy, benign partial epilepsy, and juvenile myoclonic epilepsy. If the concept of epileptic syndromes is to be practically useful, it should be limited to clusters that are unequivocally identifiable. Heterogeneous epileptic syndromes such as West syndrome or absence epilepsies give only a limited guide to prognosis but may be important in determining investigations and treatment. A classification based on syndromes has the advantage of dispensing with most assumptions required by other systems. However, it cannot cover all the clinical aspects of epilepsy and gives no guide to the pathophysiology, genetics, and etiology of a seizure disorder. The ultimate goal remains the delineation of disease entities.
Authors:
J Aicardi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Epilepsia     Volume:  29 Suppl 3     ISSN:  0013-9580     ISO Abbreviation:  Epilepsia     Publication Date:  1988  
Date Detail:
Created Date:  1989-03-27     Completed Date:  1989-03-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S1-5     Citation Subset:  IM    
Affiliation:
National Institute of Health and Medical Investigation (INSERM), Hôpital des Enfants Malades, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Epilepsy*
Humans
Syndrome

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