Document Detail

Epilepsy surgery in infancy. A review of four cases.
MedLine Citation:
PMID:  12784078     Owner:  NLM     Status:  MEDLINE    
It has been demonstrated that intractable seizures in children can be eliminated or become more responsive to anticonvulsant medication after surgical resection of the epileptogenic focus or dysfunctional hemisphere. We describe our surgical experience with 4 infants treated at Children's Healthcare of Atlanta Egleston Hospital between 1994 and 2002. All infants, ranging in age from 5 to 9 months, presented with severe seizure disorders and failed trials of anticonvulsants. All had preoperative EEG monitoring and MRI studies; 2 had PET functional imaging. One infant underwent a temporal resection for a low-grade glioma. The rest had cortical resections for malformations and dysplasia. All had improvement, with 2 infants free of seizures off medication. We argue for early intervention in severe cases, as the potential for recovery can be dramatic.
Greg Olavarria; Joseph A Petronio
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurosurgery     Volume:  39     ISSN:  1016-2291     ISO Abbreviation:  Pediatr Neurosurg     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-06-04     Completed Date:  2003-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9114967     Medline TA:  Pediatr Neurosurg     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  44-9     Citation Subset:  IM    
Copyright Information:
Copyright 2003 S. Karger AG, Basel
Department of Neurosurgery, Children's Memorial Hospital, Chicago, Ill 60614, USA.
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MeSH Terms
Epilepsy / diagnosis*,  physiopathology,  surgery*
Infant, Newborn
Magnetic Resonance Imaging
Neurosurgical Procedures*
Outcome Assessment (Health Care)
Tomography, Emission-Computed
Tomography, X-Ray Computed

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