| Epilepsy and neurocysticercosis in Atahualpa: a door-to-door survey in rural coastal Ecuador. | |
| | |
MedLine Citation:
|
PMID: 15816956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To determine the prevalence of epilepsy and the role of neurocysticercosis in the occurrence of epilepsy in Atahualpa. METHODS: We used a door-to-door survey to detect subjects with epileptic seizures, to collect a blood sample for determination of anticysticercal antibodies, and to evaluate social characteristics of the population, including household pig ownership. Neurologists examined suspected cases and a sample of negative individuals. Then patients with epilepsy, as well as age- and sex-matched controls, underwent a head computed tomography (CT) and a scalp EEG. RESULTS: The questionnaire was answered by 2,415 of 2,548 residents of Atahualpa, and cysticercosis serology was performed in 1,687 consenting individuals. Cysticercosis seroprevalence was 145 (8.6%) per 1,686). Neurologic examination confirmed 24 patients with epilepsy (crude prevalence, 9.9 per 1,000 population, and 10.8 per 1,000 when adjusted to the United States population). After adjustment by age, sex, and pig raising, positive serology was strongly associated with epilepsy (odds ratio (OR), 4.16; 95% confidence interval (CI), 1.6-11.2). CT findings compatible with neurocysticercosis were found in five patients with epilepsy and also were more frequent than in controls, although this did not reach statistical significance (five of 19 vs. one of 19; p = 0.125, McNemar's test). Besides these five cases, three other patients with epilepsy had positive serology (one with a normal CT and two who did not have a CT). CONCLUSIONS: Neurocysticercosis is associated with one-third of cases of epilepsy in Atahualpa and may be a major contributory factor for the excess fraction of epilepsy seen in this population. |
| | |
Authors:
|
Oscar H Del Brutto; Rocío Santibáñez; Luis Idrovo; Silvia Rodrìguez; Enrique Díaz-Calderón; Carlos Navas; Robert H Gilman; Fausto Cuesta; Aurelio Mosquera; Armando E Gonzalez; Victor C W Tsang; Hector H García |
Related Documents
:
|
19635686 - A clinical and magnetoencephalography study of mri-negative startle epilepsy. 15193616 - In vivo 3d mri staining of the mouse hippocampal system using intracerebral injection o... 19226336 - De novo formation of cerebral cavernous malformation in a patient with intractable epil... 15451016 - The unilateral cobalt wire model of neocortical epilepsy: a method of producing subacut... 2300356 - Magnetic resonance imaging in stage i endometrial carcinoma. 8271906 - Selective 19f mr imaging of 5-fluorouracil and alpha-fluoro-beta-alanine. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Epilepsia Volume: 46 ISSN: 0013-9580 ISO Abbreviation: Epilepsia Publication Date: 2005 Apr |
Date Detail:
|
Created Date: 2005-04-08 Completed Date: 2005-04-22 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
|
Languages: eng Pagination: 583-7 Citation Subset: IM |
Affiliation:
|
Department of Neurological Sciences, Hospital-Clínica Kennedy, Guayaquil, Ecuador. odbp@gye.satnet.net |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Age Factors Aged Child Child, Preschool Comorbidity Ecuador / epidemiology Electroencephalography Epilepsy / diagnosis, epidemiology*, etiology Female Health Surveys Humans Infant Male Middle Aged Neurocysticercosis / complications, diagnosis, epidemiology* Prevalence Questionnaires Serologic Tests Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Can you predict an immediate, complete, and sustained response to the ketogenic diet?
Next Document: Simple partial seizures with hemisensory phenomena and dysgeusia: an insular pattern.