Document Detail

Epigenetics and its implications for Psychology.
MedLine Citation:
PMID:  23336536     Owner:  NLM     Status:  In-Data-Review    
Background: Epigenetics is changing the widely accepted linear conception of genome function by explaining how environmental and psychological factors regulate the activity of our genome without involving changes in the DNA sequence. Research has identified epigenetic mechanisms mediating between environmental and psychological factors that contribute to normal and abnormal behavioral development. Method: the emerging field of epigenetics as related to psychology is reviewed. Results: the relationship between genes and behavior is reconsidered in terms of epigenetic mechanisms acting after birth and not only prenatally, as traditionally held. Behavioral epigenetics shows that our behavior could have long-term effects on the regulation of the genome function. In addition, epigenetic mechanisms would be related to psychopathology, as in the case of schizophrenia. In the latter case, it would be especially relevant to consider epigenetic factors such as life adversities (trauma, disorganized attachment, etc.) as related to its clinical manifestations, rather than genetic factors. Moreover, epigenetics implies overcoming classical dualist dichotomies such as nature-nurture, genotype-phenotype or pathogenesis-pathoplasty. Conclusions: In general, it can be stated that behavior and environment will finally take on a leading role in human development through epigenetic mechanisms.
Héctor González-Pardo; Marino Pérez Álvarez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psicothema     Volume:  25     ISSN:  1886-144X     ISO Abbreviation:  Psicothema     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101189384     Medline TA:  Psicothema     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  3-12     Citation Subset:  IM    
Universidad de Oviedo.
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