Document Detail


Epigenetics and Regeneration.
MedLine Citation:
PMID:  23197305     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
During newt lens regeneration a unique transdifferentiation event occurs. In this process, dorsal iris pigmented epithelial cells transdifferentiate into lens cells. This system should provide a new insight into cellular plasticity in basic and applied research. Recently, a series of approaches to study epigenetic reprogramming during transdifferentiation have been performed. In this review, we introduce the regulation of dynamic regulation of core-histone modifications and the emergence of an oocyte-type linker histone during transdifferentiation. Finally, we show supporting evidence that there are common strategies of reprogramming between newt somatic cell in transdifferentiation and oocytes after somatic cell nuclear transfer.
Authors:
Nobuyasu Maki; Hironobu Kimura
Related Documents :
24776535 - Printing-based assembly of quadruple-junction four-terminal microscale solar cells and ...
24926435 - Analysis of extracellular rna by digital pcr.
23668785 - Transcriptional and posttranscriptional inhibition of hmgcr and pc biosynthesis by gera...
20386145 - B cells and plasma cells in coronaries of chronically rejected cardiac transplants.
6133425 - In vitro transformation and mutation of chinese hamster cells by different sv40 nucleop...
10433835 - Fate mapping of drosophila embryonic mitotic domain 20 reveals that the larval visual s...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-30
Journal Detail:
Title:  Current topics in microbiology and immunology     Volume:  -     ISSN:  0070-217X     ISO Abbreviation:  Curr. Top. Microbiol. Immunol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0110513     Medline TA:  Curr Top Microbiol Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Institute of Protein Research, Osaka University, 3-2 Yamadaoka, Suita-Shi, Osaka, 565-0871, Japan, makinobu@protein.osaka-u.ac.jp.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Active DNA Demethylation in Plants and Animals.
Next Document:  One-Pot Ring-Closing Metathesis/1,3-Dipolar Cycloaddition through Assisted Tandem Ruthenium Catalysi...