Document Detail


The Epigenetics of Fragile X Syndrome.
MedLine Citation:
PMID:  18371387     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In this issue of Cell Stem Cell, Eiges et al. (2007) generate a human ES cell line from an embryo identified by preimplantation genetic diagnosis, and shed light on the molecular pathology of fragile X syndrome. The discovery that, upon differentiation, epigenetic modifications likely trigger silencing of the FMR1 gene sets the stage for further studies.
Authors:
Stephen T Warren
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Cell stem cell     Volume:  1     ISSN:  1875-9777     ISO Abbreviation:  Cell Stem Cell     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2008-3-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101311472     Medline TA:  Cell Stem Cell     Country:  -    
Other Details:
Languages:  ENG     Pagination:  488-489     Citation Subset:  -    
Affiliation:
Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
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