Document Detail


Epigenetic inheritance in plants.
MedLine Citation:
PMID:  17522675     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The function of plant genomes depends on chromatin marks such as the methylation of DNA and the post-translational modification of histones. Techniques for studying model plants such as Arabidopsis thaliana have enabled researchers to begin to uncover the pathways that establish and maintain chromatin modifications, and genomic studies are allowing the mapping of modifications such as DNA methylation on a genome-wide scale. Small RNAs seem to be important in determining the distribution of chromatin modifications, and RNA might also underlie the complex epigenetic interactions that occur between homologous sequences. Plants use these epigenetic silencing mechanisms extensively to control development and parent-of-origin imprinted gene expression.
Authors:
Ian R Henderson; Steven E Jacobsen
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Nature     Volume:  447     ISSN:  1476-4687     ISO Abbreviation:  Nature     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-05-24     Completed Date:  2007-06-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0410462     Medline TA:  Nature     Country:  England    
Other Details:
Languages:  eng     Pagination:  418-24     Citation Subset:  IM    
Affiliation:
Department of Molecular, Cell and Developmental Biology, Howard Hughes Medical Institute, University of California, Los Angeles, California 90095, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Arabidopsis / genetics
DNA Methylation
Epigenesis, Genetic / genetics*
Gene Expression Regulation, Plant / genetics
Gene Silencing
Plants / genetics*

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