Document Detail


Epigenetic effects of early developmental experiences.
MedLine Citation:
PMID:  22107899     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Early-life adversity can affect brain development and behavior. Emerging evidence from studies on both humans and rodents suggests that epigenetic mechanisms may play a critical role in shaping our biology in response to the quality of the environment. This article highlights the research findings suggesting that prenatal maternal stress, postnatal maternal care, and infant neglect/abuse can lead to epigenetic variation, which may have long-term effects on stress responsivity, neuronal plasticity, and behavior.
Authors:
Kathryn M A Gudsnuk; Frances A Champagne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics in perinatology     Volume:  38     ISSN:  1557-9840     ISO Abbreviation:  Clin Perinatol     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  703-17     Citation Subset:  IM    
Copyright Information:
Copyright © 2011. Published by Elsevier Inc.
Affiliation:
Department of Psychology, Columbia University, Room 406 Schermerhorn Hall, 1190 Amsterdam Avenue, New York, NY 10027, USA.
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