| Epigenetic dynamics across the cell cycle. | |
| | |
MedLine Citation:
|
PMID: 20822490 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Progression of the mammalian cell cycle depends on correct timing and co-ordination of a series of events, which are managed by the cellular transcriptional machinery and epigenetic mechanisms governing genome accessibility. Epigenetic chromatin modifications are dynamic across the cell cycle, and are shown to influence and be influenced by cell-cycle progression. Chromatin modifiers regulate cell-cycle progression locally by controlling the expression of individual genes and globally by controlling chromatin condensation and chromosome segregation. The cell cycle, on the other hand, ensures a correct inheritance of epigenetic chromatin modifications to daughter cells. In this chapter, we summarize the current knowledge on the dynamics of epigenetic chromatin modifications during progression of the cell cycle. |
| | |
Authors:
|
Tony Bou Kheir; Anders H Lund |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Essays in biochemistry Volume: 48 ISSN: 1744-1358 ISO Abbreviation: Essays Biochem. Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-09-08 Completed Date: 2010-12-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0043306 Medline TA: Essays Biochem Country: England |
Other Details:
|
Languages: eng Pagination: 107-20 Citation Subset: IM |
Affiliation:
|
Biotech Research and Innovation Centre and Centre for Epigenetics, University of Copenhagen, Ole Maaløes vej 5, 2200 Copenhagen N, Denmark. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cell Cycle / genetics* Epigenesis, Genetic* Humans Protein Processing, Post-Translational |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Non-Mendelian epigenetic heredity: gametic RNAs as epigenetic regulators and transgenerational signa...
Next Document: Epigenetic regulation of cell life and death decisions and deregulation in cancer.