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An Epigenetic Mark that Protects the Epithelial Phenotype in Health and Disease.
MedLine Citation:
PMID:  21549319     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Epithelial plasticity is crucial during embryonic development and progression of carcinomas. In this issue, Abell et al. (2011) show that acetylation on histones H2A/H2B prevents epithelial cells from undergoing epithelial-to-mesenchymal transition (EMT). Their findings also suggest that under conditions where EMT and stemness coexist, they can be independently regulated.
Authors:
Fabiana Heredia; M Angela Nieto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell stem cell     Volume:  8     ISSN:  1875-9777     ISO Abbreviation:  Cell Stem Cell     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101311472     Medline TA:  Cell Stem Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  462-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Instituto de Neurociencias CSIC-UMH, Avda. Ramón y Cajal s/n, 03550 San Juan de Alicante, Spain.
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