Document Detail

Epidural lipomatosis in steroid-treated patients.
MedLine Citation:
PMID:  1553589     Owner:  NLM     Status:  MEDLINE    
Epidural lipomatosis is a condition in which excess adipose tissue is deposited circumferentially about the spinal cord in the epidural space. It is most frequently seen in patients on chronic steroid treatment for a variety of medical problems and can present as nonspecific back pain, radiculopathy, or frank spinal cord compression. Diagnosis and treatment have generally relied on multi-level decompressive laminectomy after myelography and computed tomography. The immunocompromised state and the reported postoperative mortality (22%) of these patients, however, suggests that nonoperative therapy may be preferable whenever possible. Five cases of epidural lipomatosis are reported, and previous literature is reviewed for presentation, evaluation, and treatment of this condition.
R G Fessler; D L Johnson; F D Brown; R K Erickson; S A Reid; L Kranzler
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Spine     Volume:  17     ISSN:  0362-2436     ISO Abbreviation:  Spine     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-04-30     Completed Date:  1992-04-30     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  183-8     Citation Subset:  IM    
Department of Neurological Surgery, University of Florida, College of Medicine, Gainesville.
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MeSH Terms
Epidural Space
Lipomatosis / chemically induced*
Middle Aged
Nerve Compression Syndromes / etiology*
Prednisone / adverse effects*,  therapeutic use
Spinal Cord Compression / etiology
Spinal Nerve Roots*
Reg. No./Substance:
Comment In:
Spine (Phila Pa 1976). 1992 Oct;17(10):1268   [PMID:  1440025 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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