Document Detail

Epididymo-orchitis following intravesical bacillus Calmette-Guérin therapy.
MedLine Citation:
PMID:  10772435     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe a case of epididymo-orchitis that developed four years after treatment with intravesical bacillus Calmette-Guérin (BCG) and to review the incidence of this adverse effect. DATA SOURCES: Information about the patient was obtained from the medical chart. A MEDLINE search of English-language literature (from January 1976 to April 1999) was conducted. STUDY SELECTION: All case reports of BCG-related epididymo-orchitis were evaluated. Review articles describing complications of BCG therapy for bladder cancer and the prevention and treatment of these complications were reviewed. DATA EXTRACTION: Studies were evaluated for reports of BCG-related epididymo-orchitis and its treatment. DATA SYNTHESIS: Our case report is compared with others reported in the literature. The incidence of BCG-associated epididymoorchitis is rare. CONCLUSIONS: Epididymo-orchitis should be considered as a late complication of BCG therapy for bladder cancer. Proper patient selection may help decrease the risk of complications from BCG therapy.
J J Menke; J R Heins
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Annals of pharmacotherapy     Volume:  34     ISSN:  1060-0280     ISO Abbreviation:  Ann Pharmacother     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-06-23     Completed Date:  2000-06-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9203131     Medline TA:  Ann Pharmacother     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  479-82     Citation Subset:  IM    
South Dakota State University, Brookings, USA.
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MeSH Terms
Adjuvants, Immunologic / adverse effects*,  therapeutic use
Administration, Intravesical
BCG Vaccine / adverse effects*,  therapeutic use
Carcinoma, Transitional Cell / complications,  drug therapy
Epididymitis / chemically induced*,  complications,  epidemiology
Orchitis / chemically induced*,  complications,  epidemiology
Urinary Bladder Neoplasms / complications,  drug therapy
Reg. No./Substance:
0/Adjuvants, Immunologic; 0/BCG Vaccine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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