| Epidermolysis bullosa in the eastern province of Saudi Arabia. | |
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MedLine Citation:
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PMID: 8407073 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Epidermolysis bullosa is recognized to be rare, but its prevalence in the Eastern Province of Saudi Arabia had not been previously established. METHODS: We reviewed 49,902 dermatology cases seen in our clinic over a 7-year period (1984 through 1990) and carried out a therapeutic trial of oral phenytoin in three severe cases of epidermolysis bullosa dystrophica (Recessive dystrophic type). RESULTS: Sixteen cases of epidermolysis bullosa were found in this series, ten (62.5%) of which were of the dermolytic type (epidermolysis bullosa dystrophica), and four (25%) of the epidermolytic type (epidermolysis bullosa simplex). Parental consanguinity was established in fourteen (87.5%) of these cases. All ten cases of epidermolysis bullosa dystrophica developed complications. Three severe cases were treated with oral phenytoin and managed with meticulous nursing and nutrition with blended foods and protein and vitamin supplements and responded satisfactorily. CONCLUSIONS: This study confirmed the rarity of epidermolysis bullosa in this province (population 3,000,000), and demonstrated the usefulness of oral phenytoin therapy, meticulous nursing, and good nutrition in the management of epidermolysis bullosa dystrophica. |
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Authors:
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A A Abahussein; A A al-Zayir; W Z Mostafa; A N Okoro |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of dermatology Volume: 32 ISSN: 0011-9059 ISO Abbreviation: Int. J. Dermatol. Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1993-10-28 Completed Date: 1993-10-28 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 0243704 Medline TA: Int J Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 579-81 Citation Subset: IM |
Affiliation:
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Department of Dermatology, College of Medicine and Medical Sciences, King Faisal University, Dammam, Saudi Arabia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Child, Preschool Epidermolysis Bullosa / epidemiology*, genetics, therapy Female Humans Infant Infant, Newborn Male Phenytoin / therapeutic use Saudi Arabia / epidemiology |
| Chemical | |
Reg. No./Substance:
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57-41-0/Phenytoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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