Document Detail

Epidemiology of stillbirth and fetal central nervous system injury.
MedLine Citation:
PMID:  18652919     Owner:  NLM     Status:  MEDLINE    
The epidemiology of stillbirth and fetal central nervous system (CNS) injury is described with some emphasis on maternal and feto-placental risk factors. To maximize utility of the discussion and because it also represents the classical manifestation of fetal CNS injury, we have selected cerebral palsy (CP) to illustrate the epidemiologic aspects of injury to the fetal CNS in general. While trends in stillbirth rates have modestly decreased over time, those of CP seem to be increasing. Interestingly, both stillbirth and CP share traditional as well as emerging risk factors lending credence to the hypothesis that fetuses that would previously have been stillborn are increasingly surviving albeit with some form of morbidity. The existence of shared risk factors also suggests that in some cases of stillbirth fetal CNS injury precedes the in utero fetal demise. Pregnant women bearing these risk indicators represent potential candidates for appropriate and tailored protocols for antenatal fetal testing.
Hamisu M Salihu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Seminars in perinatology     Volume:  32     ISSN:  0146-0005     ISO Abbreviation:  Semin. Perinatol.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-25     Completed Date:  2008-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801132     Medline TA:  Semin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  232-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL, USA.
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MeSH Terms
Brain Diseases / complications,  epidemiology*
Cerebral Palsy / epidemiology*
Fetal Diseases / epidemiology*
Risk Factors
Stillbirth / epidemiology*
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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