| Epidemiology of severe pneumonia caused by Legionella longbeachae, Mycoplasma pneumoniae, and Chlamydia pneumoniae: 1-year, population-based surveillance for severe pneumonia in Thailand. | |
| | |
MedLine Citation:
|
PMID: 18190309 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Legionella species, Mycoplasma pneumoniae, and Chlamydia pneumoniae are recognized as important causes of pneumonia in high-income countries, but their significance in middle-income countries, such as Thailand, is unknown. METHODS: Population-based surveillance identified inpatient 3489 cases of clinically-defined pneumonia in a rural Thai province for 1 year. Patients who had a chest radiograph performed (for 2059 cases of pneumonia) were enrolled in an etiology study (which included 755 cases of pneumonia among 738 patients). Paired serum, nasopharyngeal swab, and urine specimens were obtained for diagnostic immunologic and molecular tests. Patients aged <18 years were not systematically tested for Legionella species. We report a lower limit of incidence (observed incidence) and an upper limit extrapolated to persons not tested or not enrolled in the study. RESULTS: The incidence of pneumonia due to Legionella longbeachae requiring hospitalization was 5-29 cases per 100,000 population. No case of Legionella pneumophila pneumonia was observed. The definite C. pneumoniae pneumonia incidence was 3-23 cases per 100,000 population; rates were highest among patients aged <1 year (18-166 cases per 100,000 population) and those aged >or=70 years (23-201 cases per 100,000 population). M. pneumoniae pneumonia had a similar age distribution, with an overall incidence of 6-44 cases per 100,000 population. These pathogens were associated with 15% of all cases of pneumonia. A nonsignificantly higher proportion of patients with pneumonia associated with L. longbeachae, compared with patients with pneumonia associated with M. pneumoniae or C. pneumoniae, required supplemental oxygen or mechanical ventilation (45% vs. 18%; P<.1). Among patients with atypical pneumonia, only 15% received antibiotics with activity against the associated pathogen. CONCLUSION: M. pneumoniae, C. pneumoniae, and L. longbeachae, but not L. pneumophila, are frequently associated with severe pneumonia in rural Thailand. Few patients receive antibiotics that cover atypical pathogens. |
| | |
Authors:
|
Christina R Phares; Piyada Wangroongsarb; Somrak Chantra; Wantana Paveenkitiporn; Maria-Lucia Tondella; Robert F Benson; W Lanier Thacker; Barry S Fields; Matthew R Moore; Julie Fischer; Scott F Dowell; Sonja J Olsen |
Related Documents
:
|
11858379 - Meningitis due to salmonella in preterm neonates. 12850229 - Endogenous bacterial endophthalmitis: a 17-year prospective series and review of 267 re... 20358139 - Deafness due to haemorrhagic labyrinthitis and a review of relapses in streptococcus su... 7387469 - Hemiplegic migraine associated with an aseptic meningeal reaction. 17445319 - Icd-10 codes are a valid tool for identification of pneumonia in hospitalized patients ... 301699 - Intrafamily spread of haemophilus type b infections. 12141959 - Outbreak of serogroup w135 meningococcal disease after the hajj pilgrimage, europe, 2000. 643959 - Use of an encircling silicone rubber string for the correction of lagophthalmos. 20354829 - Primary malignant fibrous histiocytoma of spleen with spontaneous rupture: a case repor... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 45 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2007 Dec |
Date Detail:
|
Created Date: 2008-01-14 Completed Date: 2008-03-11 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
|
Languages: eng Pagination: e147-55 Citation Subset: IM |
Affiliation:
|
Epidemic Intelligence Service Program, Office of Workforce and Career Development, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. CPhares@cdc.gov |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Age Factors Aged Child, Preschool Chlamydophila Infections / epidemiology, microbiology Chlamydophila pneumoniae* Female Humans Incidence Infant Infant, Newborn Legionella longbeachae* Legionellosis / epidemiology, microbiology Male Middle Aged Mycoplasma pneumoniae* Pneumonia, Bacterial / complications, epidemiology*, microbiology Pneumonia, Mycoplasma / epidemiology, microbiology Population Surveillance* Sex Factors Thailand / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diagnostic challenges of tuberculosis peritonitis in patients with and without end-stage renal failu...
Next Document: Fungal internal carotid artery aneurysms: successful embolization of an Aspergillus-associated case ...