| Epidemiology of ophthalmia neonatorum in Kenya. | |
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MedLine Citation:
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PMID: 2877285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a Nairobi hospital where ocular prophylaxis against ophthalmia neonatorum has been discontinued, 1,019 women were screened for Neisseria gonorrhoeae and Chlamydia trachomatis during labour and 7 and 28 days postpartum. The prevalence of gonococcal infection was 7% and that of chlamydial was 29%. 52.4% of gonococcal isolates produced penicillinase. The incidence of ophthalmia neonatorum was 23.2 per 100 live births, and incidences of gonococcal and chlamydial ophthalmia were 3.6 and 8.1 per 100 live births, respectively. Of 181 cases of neonatal conjunctivitis, 31% were caused by C trachomatis, 12% by N gonorrhoeae, and 3% by both. In 67 babies exposed to maternal gonococcal infection and 201 exposed to maternal chlamydial infection, rates of transmission to the eye were 42% and 31%, respectively, and to the throat were 7% and 2%. Gonococcal transmission rate was higher in mothers with concomitant chlamydial infection (68%; p = 0.01). Postpartum endometritis was associated with ophthalmia neonatorum (p less than 0.001). Ocular prophylaxis at birth for gonococcal ophthalmia should be reintroduced. |
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Authors:
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M Laga; F A Plummer; H Nzanze; W Namaara; R C Brunham; J O Ndinya-Achola; G Maitha; A R Ronald; L J D'Costa; V B Bhullar |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Lancet Volume: 2 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1986 Nov |
Date Detail:
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Created Date: 1986-12-17 Completed Date: 1986-12-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1145-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cervix Uteri / microbiology Chlamydia Infections / epidemiology, transmission Chlamydia trachomatis / isolation & purification Conjunctiva / microbiology Female Gonorrhea / epidemiology, transmission Humans Infant, Newborn Kenya Neisseria gonorrhoeae / isolation & purification Ophthalmia Neonatorum / epidemiology* Pregnancy Pregnancy Complications, Infectious / microbiology Prospective Studies Risk |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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