Document Detail

Epidemiology of ophthalmia neonatorum in Kenya.
MedLine Citation:
PMID:  2877285     Owner:  NLM     Status:  MEDLINE    
In a Nairobi hospital where ocular prophylaxis against ophthalmia neonatorum has been discontinued, 1,019 women were screened for Neisseria gonorrhoeae and Chlamydia trachomatis during labour and 7 and 28 days postpartum. The prevalence of gonococcal infection was 7% and that of chlamydial was 29%. 52.4% of gonococcal isolates produced penicillinase. The incidence of ophthalmia neonatorum was 23.2 per 100 live births, and incidences of gonococcal and chlamydial ophthalmia were 3.6 and 8.1 per 100 live births, respectively. Of 181 cases of neonatal conjunctivitis, 31% were caused by C trachomatis, 12% by N gonorrhoeae, and 3% by both. In 67 babies exposed to maternal gonococcal infection and 201 exposed to maternal chlamydial infection, rates of transmission to the eye were 42% and 31%, respectively, and to the throat were 7% and 2%. Gonococcal transmission rate was higher in mothers with concomitant chlamydial infection (68%; p = 0.01). Postpartum endometritis was associated with ophthalmia neonatorum (p less than 0.001). Ocular prophylaxis at birth for gonococcal ophthalmia should be reintroduced.
M Laga; F A Plummer; H Nzanze; W Namaara; R C Brunham; J O Ndinya-Achola; G Maitha; A R Ronald; L J D'Costa; V B Bhullar
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1986-12-17     Completed Date:  1986-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1145-9     Citation Subset:  AIM; IM    
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MeSH Terms
Cervix Uteri / microbiology
Chlamydia Infections / epidemiology,  transmission
Chlamydia trachomatis / isolation & purification
Conjunctiva / microbiology
Gonorrhea / epidemiology,  transmission
Infant, Newborn
Neisseria gonorrhoeae / isolation & purification
Ophthalmia Neonatorum / epidemiology*
Pregnancy Complications, Infectious / microbiology
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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