| Epidemiology of nosocomial infections in selected neonatal intensive care units in Colombia, South America. | |
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MedLine Citation:
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PMID: 15944725 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The epidemiology of nosocomial infections (NI) in neonatal intensive care units in developing countries has been poorly studied. We conducted a prospective study in selected neonatal units in Colombia, SA, to describe the incidence rate, causative organisms, and interinstitutional differences. STUDY DESIGN: Data were collected prospectively from February 20 to August 30, 2001 from eight neonatal units. NI was defined as culture-proven infection diagnosed after 72 h of hospitalization, resulting in treatment with antibiotics for >3 days. Linear regression models were used to describe associations between institutional variables and NI rates. RESULTS: A total of 1504 infants were hospitalized for more than 72 h, and therefore, at risk for NI. Of all, 127 infections were reported among 80 patients (5.3%). The incidence density rate was 6.2 per 1000 patient-days. Bloodstream infections accounted for 78% of NIs. Gram-negative organisms predominated over gram-positive organisms (55 vs 38%) and were prevalent in infants < or =2000 g (54%). The most common pathogens were Staphylococcus epidermidis (26%) and Klebsiella pneumonia (12%). CONCLUSION: Gram-negative organisms predominate in Colombia among infants <2000 g. The emergence of gram-negative organisms and their associated risk factors requires further study. |
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Authors:
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Meica M Efird; Mario A Rojas; Juan M Lozano; Carl L Bose; María X Rojas; Martín A Rondón; Gloria Ruiz; Juan G Piñeros; Catherine Rojas; Guillermo Robayo; Angela Hoyos; Maria E Gosendi; Hernan Cruz; Angela Leon |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 25 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-07-27 Completed Date: 2005-11-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 531-6 Citation Subset: IM |
Affiliation:
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University of North Carolina (M.M.E., M.A.R., C.L.B.), Chapel Hill, North Carolina, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Colombia
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epidemiology Cross Infection / epidemiology* Gram-Negative Bacterial Infections / epidemiology Humans Incidence Infant, Newborn Intensive Care Units, Neonatal / statistics & numerical data* Linear Models Prevalence Prospective Studies |
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