Document Detail


Epidemiology of nosocomial infections in selected neonatal intensive care units in Colombia, South America.
MedLine Citation:
PMID:  15944725     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The epidemiology of nosocomial infections (NI) in neonatal intensive care units in developing countries has been poorly studied. We conducted a prospective study in selected neonatal units in Colombia, SA, to describe the incidence rate, causative organisms, and interinstitutional differences. STUDY DESIGN: Data were collected prospectively from February 20 to August 30, 2001 from eight neonatal units. NI was defined as culture-proven infection diagnosed after 72 h of hospitalization, resulting in treatment with antibiotics for >3 days. Linear regression models were used to describe associations between institutional variables and NI rates. RESULTS: A total of 1504 infants were hospitalized for more than 72 h, and therefore, at risk for NI. Of all, 127 infections were reported among 80 patients (5.3%). The incidence density rate was 6.2 per 1000 patient-days. Bloodstream infections accounted for 78% of NIs. Gram-negative organisms predominated over gram-positive organisms (55 vs 38%) and were prevalent in infants < or =2000 g (54%). The most common pathogens were Staphylococcus epidermidis (26%) and Klebsiella pneumonia (12%). CONCLUSION: Gram-negative organisms predominate in Colombia among infants <2000 g. The emergence of gram-negative organisms and their associated risk factors requires further study.
Authors:
Meica M Efird; Mario A Rojas; Juan M Lozano; Carl L Bose; María X Rojas; Martín A Rondón; Gloria Ruiz; Juan G Piñeros; Catherine Rojas; Guillermo Robayo; Angela Hoyos; Maria E Gosendi; Hernan Cruz; Angela Leon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  25     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-27     Completed Date:  2005-11-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  531-6     Citation Subset:  IM    
Affiliation:
University of North Carolina (M.M.E., M.A.R., C.L.B.), Chapel Hill, North Carolina, USA.
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MeSH Terms
Descriptor/Qualifier:
Colombia / epidemiology
Cross Infection / epidemiology*
Gram-Negative Bacterial Infections / epidemiology
Humans
Incidence
Infant, Newborn
Intensive Care Units, Neonatal / statistics & numerical data*
Linear Models
Prevalence
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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