| Epidemiology of neuroleptic malignant syndrome. | |
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MedLine Citation:
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PMID: 10367179 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors reviewed the trends in the incidence of neuroleptic malignant syndrome (NMS) in studies recently reported in various countries. Possible reasons for the differences in reported incidences were considered. The authors identified publications in English (and their cross-references) that estimated the incidence of NMS with a retrospective or prospective design. They compared the incidence in studies from the United States with those from other countries. The initial retrospective studies from the United States reported higher incidence rates of NMS than did similar studies from elsewhere. More recent prospective studies from the United States report a much lower incidence. Neuroleptic malignant syndrome remains a rare complication of psychotropic treatment if the syndrome is defined stringently. The high incidence reported in earlier studies in the United States can be explained by retrospective study design, loose diagnostic criteria, adherence to an amorphous "spectrum concept," and clinical practices in vogue. |
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Authors:
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Adityanjee; Y A Aderibigbe; T Mathews |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical neuropharmacology Volume: 22 ISSN: 0362-5664 ISO Abbreviation: Clin Neuropharmacol Publication Date: 1999 May-Jun |
Date Detail:
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Created Date: 1999-07-21 Completed Date: 1999-07-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7607910 Medline TA: Clin Neuropharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 151-8 Citation Subset: IM |
Affiliation:
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Dayton VAMC/Wright State University School of Medicine, Ohio, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Incidence Mental Disorders / drug therapy Neuroleptic Malignant Syndrome / diagnosis, epidemiology* Prospective Studies Retrospective Studies |
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