| Epidemiology of multiple system atrophy. ESGAP Consortium. European Study Group on Atypical Parkinsonisms. | |
| | |
MedLine Citation:
|
PMID: 11487219 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Multiple system atrophy (MSA) is a form of atypical parkinsonism with unknown etiology. The epidemiological studies conducted up to now on this disease are scarce. The incidence rate is about 0.6 cases per 100,000 persons per year. The prevalence rates show 4-5 cases per 100,000 persons. In Italy, about 4,900 prevalent cases have been estimated. The mean onset age is about 54 years; the median survival is 7-9 years. Only one case-control study has been performed on this disease. This study showed an increased risk of MSA associated with occupational exposure to organic solvents, plastic monomers and additives, pesticides and metals. Smoking habits seem to be less frequent in MSA cases (as in Parkinson's disease cases) than in healthy controls. Quinn's clinical criteria and those of the Consensus Conference promoted by the American Academy of Neurology are in fair agreement. We have performed a case-control study on 73 MSA cases, 146 hospital controls and 73 population controls. |
| | |
Authors:
|
N Vanacore; V Bonifati; G Fabbrini; C Colosimo; G De Michele; R Marconi; D Nicholl; N Locuratolo; G Talarico; S Romano; F Stocchi; U Bonuccelli; M De Mari; P Vieregge; G Meco; |
Related Documents
:
|
8116599 - Should we consider a subject's knowledge of the etiologic hypothesis in the analysis of... 1637899 - Reporting and selection bias in case-control studies of congenital malformations. 15006289 - The alien hand: cases, categorizations, and anatomical correlates. 10194079 - Human herpesvirus 6 dna in cerebrospinal fluid specimens from allogeneic bone marrow tr... 3700579 - Extensions of analytic methods for nested and population-based incident case-control st... 1667259 - Cyclic nucleotides in chicken bursocytes and thymocytes. 12775979 - Childhood bullous pemphigoid: a clinicopathologic study and review of the literature. 9563929 - Abdominal cocoon in a man: preoperative diagnosis and literature review. 1555379 - Case report: disseminated pneumocystis carinii infection in a patient with the acquired... |
Publication Detail:
|
Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology Volume: 22 ISSN: 1590-1874 ISO Abbreviation: Neurol. Sci. Publication Date: 2001 Feb |
Date Detail:
|
Created Date: 2001-08-06 Completed Date: 2001-12-13 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 100959175 Medline TA: Neurol Sci Country: Italy |
Other Details:
|
Languages: eng Pagination: 97-9 Citation Subset: IM |
Affiliation:
|
Department of Neurological Sciences, La Sapienza University, Rome, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age of Onset Case-Control Studies Diagnosis, Differential Environmental Exposure Female Genetic Predisposition to Disease / epidemiology Humans Incidence Male Multiple System Atrophy / epidemiology*, etiology, physiopathology Point Mutation / genetics Prevalence Questionnaires Sex Factors Smoking / adverse effects Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Identification of a novel primary torsion dystonia locus (DYT13) on chromosome 1p36 in an Italian fa...
Next Document: Verification of bacterial killing effects of cage wash time and temperature combinations using stand...