Document Detail

Epidemiology and management of essential tremor in children.
MedLine Citation:
PMID:  19725596     Owner:  NLM     Status:  MEDLINE    
Essential tremor (ET) is a common, often familial, movement disorder characterized by tremor of the limbs, head, and voice. Epidemiological surveys indicate that up to 5% of the adult population has ET, and 5-30% of adults with ET report symptom onset during childhood. There is, however, little published regarding ET in the pediatric population, and no prospective studies targeted specifically to children. Retrospective studies from subspecialty movement disorder clinics indicate that childhood-onset ET is usually hereditary, begins at a mean age of 6 years, and affects boys three times as often as girls. While ET occasionally results in disability during childhood, only one-quarter of children seeing a neurologist for ET require pharmacotherapy. Small case series suggest that propranolol is effective in approximately 50% of children with ET, but controlled treatment trials are lacking.
Joseph Ferrara; Joseph Jankovic
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Paediatric drugs     Volume:  11     ISSN:  1174-5878     ISO Abbreviation:  Paediatr Drugs     Publication Date:  2009  
Date Detail:
Created Date:  2009-09-03     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883685     Medline TA:  Paediatr Drugs     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  293-307     Citation Subset:  IM    
Parkinson Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA.
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use*
Clinical Trials as Topic
Diagnosis, Differential
Essential Tremor / drug therapy*,  epidemiology,  physiopathology
Middle Aged
Propranolol / therapeutic use*
Risk Factors
Sex Factors
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 525-66-6/Propranolol

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