Document Detail

Epidemiology of infantile hydrocephalus in Sweden. III. Origin in preterm infants.
MedLine Citation:
PMID:  2440228     Owner:  NLM     Status:  MEDLINE    
The aetiology of infantile hydrocephalus (IH) was studied in a population-based series of 61 children with IH born 1967-82 at less than 37 weeks of gestation. A prenatal origin was present in 17 children (28%), a pre- and perinatal in 17 (28%), a perinatal in 26 (43%) and a postnatal in one (1%). The predominant single cause was postaemorrhagic IH, which was diagnosed in 19 (31%). In addition, an undiagnosed cerebral haemorrhage was considered to be the cause in another 25%. The outcome differed between pathogenetic groups. Children with a clear onset of IH (pre-, peri- or postnatal) were found to be at high risk for early death or multiple impairments. Sixteen of 39 (41%) within these groups had died before 2 years of age and 18 of the 23 (78%) survivors showed major neurological dysfunction. This contrasted to no mortality and 41% major dysfunction in children with a less clear onset of IH. A new subgroup consisting of infants born before 28 weeks of gestation emerged in the early 1980s. All infants with IH in this group developed a severe multihandicap condition.
E Fernell; B Hagberg; G Hagberg; L von Wendt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  76     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-08-11     Completed Date:  1987-08-11     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  418-23     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Developmental Disabilities / etiology
Hydrocephalus / epidemiology,  etiology*
Infant Mortality
Infant, Newborn
Infant, Premature, Diseases / epidemiology,  etiology*
Mental Retardation / etiology

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