Document Detail

Epidemiology and etiologic diagnosis of infectious keratitis in Uberlandia, Brazil.
MedLine Citation:
PMID:  20175055     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To study risk factors, microbiological characteristics, and clinical course of nonviral infectious keratitis diagnosed in a referral service of ophthalmology. METHODS: A total of 65 charts of patients with microbial keratitis were retrospectively reviewed at the Clinical Hospital of Federal University of Uberlandia, Brazil, from July 2001 through August 2004. All cases were submitted to microbiological tests and treated according to local protocol. Risk factors, clinical course, therapeutic keratoplasty, and visual outcomes were analyzed. RESULTS: The mean age of patients was 45.9 years (2-83 years) and male to female ratio 2.6:1. Symptoms at presentation ranged from 1-3 days in 16 patients out of 65 (24.61%), 4-7 days in 19 cases (19/65; 29.23%), and more than 7 days in 27 patients (27/65; 41.53%). The major risk factor was trauma (28/65; 40%), predominantly by organic material. A total of 32 eyes out of 65 (49.23%) were culture positive. Fungi were the most common isolates (18/32; 56.25%), being headed by Fusarium sp. (11/65; 16.92%), and the most common bacteria was Streptococcus pneumoniae (7/65; 10.77%). Final visual acuity was equal to or better than 20/60 in 20 patients out of 65 (30.77%), between 20/60 and 20/400 in 7 patients (7/65; 10.77%), and worse than 20/400 in 35 patients out of 65 (53.85%). A total of 48 eyes out of 65 (73.84%) presented corneal scar, 12 eyes (12/65; 18.46%) needed therapeutic penetrating keratoplasty, and 2 eyes (2/65; 3.08%) were eviscerated. CONCLUSIONS: The high incidence of fungal keratitis in the studied population shows their vulnerability to such infections, which may result in devastating visual outcomes.
Rafael Lacerdda Furlanetto; Eduardo G V Andreo; Ion? G A Finotti; Enyr S Arcieri; Magno A Ferreira; Flavio J Rocha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  20     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-04-21     Completed Date:  2010-06-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  498-503     Citation Subset:  IM    
Department of Ophthalmology, Federal University of Uberlandia, Minas Gerais - Brazil.
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MeSH Terms
Aged, 80 and over
Anti-Infective Agents / therapeutic use
Bacteria / isolation & purification
Brazil / epidemiology
Cefazolin / therapeutic use
Child, Preschool
Ciprofloxacin / therapeutic use
Cornea / microbiology
Corneal Ulcer / drug therapy,  epidemiology*,  microbiology
Drug Therapy, Combination
Eye Infections, Bacterial / drug therapy,  epidemiology*,  microbiology
Eye Infections, Fungal / drug therapy,  epidemiology*,  microbiology
Fungi / isolation & purification
Middle Aged
Retrospective Studies
Risk Factors
Visual Acuity
Reg. No./Substance:
0/Anti-Infective Agents; 25953-19-9/Cefazolin; 85721-33-1/Ciprofloxacin

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