| Epidemiology and control of vancomycin-resistant enterococci in a regional neonatal intensive care unit. | |
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MedLine Citation:
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PMID: 10223689 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: After the occurrence of two cases of bloodstream infection with vancomycin-resistant enterococci (VRE) in our regional neonatal intensive care unit, we studied the epidemiology of VRE and applied extensive infection control measures to the unit to control VRE transmission. METHODS: Infection control measures applied to the unit included weekly surveillance for VRE colonization; education; cohorting of VRE-positive, VRE-negative and VRE-exposed babies with separate personnel and equipment for each group; use of gowns and gloves on room entry; and hand washing before and after each patient contact. Risk factors for VRE colonization were determined with a stepwise logistic regression model. RESULTS: Thirty-three (40.2%) babies became colonized with VRE. The VRE colonization rate was reduced from 67% to 7% after implementation of infection control measures. Prolonged antimicrobial treatment and low birth weight were significantly associated with an increased risk of VRE colonization. CONCLUSION: VRE can spread rapidly among newborns in a regional neonatal intensive care unit. Strict infection control measures can reduce the rate of VRE colonization among neonates. |
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Authors:
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R K Malik; M A Montecalvo; M R Reale; K Li; M Maw; J L Munoz; C Gedris; K van Horn; K A Carnevale; M H Levi; H S Dweck |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Pediatric infectious disease journal Volume: 18 ISSN: 0891-3668 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 1999 Apr |
Date Detail:
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Created Date: 1999-06-03 Completed Date: 1999-06-03 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 352-6 Citation Subset: IM |
Affiliation:
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Division of Neonatology, New York Medical College, Valhalla 10595, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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pharmacology* Cross Infection / epidemiology, prevention & control* Drug Resistance, Microbial Electrophoresis, Gel, Pulsed-Field Enterococcus / drug effects*, isolation & purification Gram-Positive Bacterial Infections / drug therapy, epidemiology, prevention & control* Humans Infant, Newborn Infection Control Intensive Care Units, Neonatal Risk Factors Vancomycin / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 1404-90-6/Vancomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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