Document Detail


Epidemiology and control of SARS in Singapore.
MedLine Citation:
PMID:  16829997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe acute respiratory syndrome (SARS) was imported into Singapore in late February 2003 by a local resident who returned from a holiday in Hong Kong and started an outbreak in the hospital where she was admitted on 1 March 2003. The disease subsequently spread to 4 other healthcare institutions and a vegetable wholesale centre. During the period between March and May 2003, 238 probable SARS cases, including 8 imported cases and 33 deaths, were reported. Transmission within the healthcare and household settings accounted for more than 90% of the cases. Factors contributing to the spread of infection included the failure to recognise the high infectivity of this novel infection, resulting in a delay in isolating initial cases and contacts and the implementation of personal protective measures in healthcare institutions; and the super-spreading events by 5 index cases, including 3 with co-morbid conditions presenting with atypical clinical manifestations of SARS. Key public health measures were directed at prevention and control within the community and hospitals, and the prevention of imported and exported cases. An isolated laboratory-acquired case of SARS was reported on 8 September 2003. Based on the lessons learnt, Singapore has further strengthened its operational readiness and laboratory safety to respond to SARS, avian flu and other emerging diseases.
Authors:
Kee-Tai Goh; Jeffery Cutter; Bee-Hoon Heng; Stefan Ma; Benjamin K W Koh; Cynthia Kwok; Cheong-Mui Toh; Suok-Kai Chew
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  35     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-07-10     Completed Date:  2006-11-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  301-16     Citation Subset:  IM    
Affiliation:
Communicable Diseases, Health Regulation Division, Ministry of Health, Singapore. goh_kee_tai@moh.gov.sg
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Disease Outbreaks / prevention & control,  statistics & numerical data*
Disease Transmission, Infectious / prevention & control*
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
Retrospective Studies
Severe Acute Respiratory Syndrome / epidemiology*,  transmission
Singapore / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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