Document Detail


Epidemiology of atrial fibrillation.
MedLine Citation:
PMID:  19562528     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Atrial fibrillation is the most common sustained cardiac arrhythmia in the general population. Unfortunately, current treatment strategies aiming at the elimination of atrial fibrillation have limited long term success rates and significant risks. In this context, recent publications have provided many insights on potentially treatable risk factors for the occurrence of atrial fibrillation, such as alcohol, blood pressure, obesity, inflammation and nutritional factors. In this review, we summarise the current evidence on these risk factors and indicate areas in need of further investigation. The current evidence shows that blood pressure, hypertension and obesity seem to play a key role in the pathogenesis of atrial fibrillation. Preliminary evidence also suggests that inflammation is an important mediator of these associations. Knowledge of these interrelationships may eventually help to develop new treatment strategies and decrease the burden of atrial fibrillation in the general population.
Authors:
D Conen; S Osswald; C M Albert
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Swiss medical weekly     Volume:  139     ISSN:  1424-7860     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-29     Completed Date:  2009-08-26     Revised Date:  2011-06-01    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  346-52     Citation Subset:  IM    
Affiliation:
Department of Medicine, Cardiology Division, University Hospital, Basel, Switzerland. conend@uhbs.ch
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / etiology*
Female
Humans
Hypertension / complications*
Male
Obesity / complications*
Risk Factors
Grant Support
ID/Acronym/Agency:
R21 HL093613-01A2/HL/NHLBI NIH HHS; R21 HL093613-02/HL/NHLBI NIH HHS

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