Document Detail


Epidemiology of anaphylaxis.
MedLine Citation:
PMID:  23344669     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Anaphylaxis is the most severe manifestation of a mast cell dependent hypersensitivity reaction. Recent data on epidemiology indicate that food and drug induced anaphylaxis has increased within the last years. The epidemiological data on anaphylaxis vary throughout the world as the overall incidence and also relevant elicitors depend on different endogenous, but also exogenous factors (e.g. ICD-code, life style, comorbidities). Data from the anaphylaxis registry has shown that venom, drugs and foods are the most frequent elicitors for anaphylaxis within German-speaking countries, while the ranking of the elicitors is age-dependent. Risk factors for anaphylaxis are comorbidities like asthma or mastocytosis or other circumstances, which can increase either the relative risk or the severity. Further risk factors are age, gender and the concomitant intake of drugs like ACE inhibitors or acetylsalicylic acid but also exercise. Data on the clinical epidemiology of anaphylaxis are essential to follow up the most frequent elicitors and risk factors over time and accumulate data about diagnostic and therapeutic procedures in patients suffering from a potential fatal manifestation of an IgE-dependent disease. The anaphylaxis registry within the German-speaking area achieved to provide data of the most frequent elicitors, risk factors and the medical treatment from affected individuals to optimize the management of patients with anaphylaxis.
Authors:
M Worm
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-25
Journal Detail:
Title:  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete     Volume:  -     ISSN:  1432-1173     ISO Abbreviation:  Hautarzt     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372755     Medline TA:  Hautarzt     Country:  -    
Other Details:
Languages:  GER     Pagination:  -     Citation Subset:  -    
Affiliation:
Klinik für Dermatologie, Venerologie und Allergologie, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Deutschland, margitta.worm@charite.de.
Vernacular Title:
Epidemiologie der Anaphylaxie.
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