Document Detail


Epidemiology of Haemophilus influenzae type b disease in France.
MedLine Citation:
PMID:  8447173     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Results are reported of an epidemiological study which spanned ten years and was carried out in two French departments. A total of 277 cases of Hib disease occurring in children < 5 years old are reported and, in this age group, the incidence is evaluated at 21/100,000. Meningitis accounted for 64% of infections and epiglottitis for 7%. While the overall mortality rate was 3.3%, death was secondary to meningitis in 7/8 cases. Sequelae, which were all related to meningitis, were major in 1.2% of cases, severe in 9% of cases, and involved some hearing loss in 3.3% of cases. The monitoring networks set up in the two departments were characterized by sensitivities of 87 and 94%, respectively. They should prove useful in assessing the impact of vaccination, when large-scale implementation of vaccination has spread to both departments.
Authors:
P Reinert; A Liwartowski; H Dabernat; C Guyot; J Boucher; C Carrere
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vaccine     Volume:  11 Suppl 1     ISSN:  0264-410X     ISO Abbreviation:  Vaccine     Publication Date:  1993  
Date Detail:
Created Date:  1993-04-08     Completed Date:  1993-04-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8406899     Medline TA:  Vaccine     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S38-42     Citation Subset:  IM    
Affiliation:
University Department of Public Health, Faculty of Medicine, University of Creteil, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Drug Resistance, Microbial
Epiglottitis / epidemiology
Female
France / epidemiology
Haemophilus Infections / complications,  epidemiology*
Haemophilus influenzae* / classification,  drug effects
Hearing Disorders / etiology
Humans
Infant
Longitudinal Studies
Male
Meningitis, Haemophilus / complications,  epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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