Document Detail

Epidemiological study of reptured intracranial aneurysms in the Saguenay-Lac-Saint-Jean region (Quebec, Canada).
MedLine Citation:
PMID:  8862839     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Using a population-based register of the Saguenay-Lac-Saint-Jean region (Quebec, Canada), the genealogical reconstruction of 533 individuals with intracranial aneurysm (IA) showed a familial aggregation (the presence of aneurysm in two or more first- to third-degree relatives) for 159 (29.8%) of them; this proportion is much higher than reported elsewhere. OBJECTIVE: As part of an ongoing project to assess a genetic predisposition to intracranial aneurysms in the Saguenay-Lac-Saint-Jean population, the objective of the present study was to determine whether age-specific rates of reputed cerebral aneurysms were higher than in other populations. DESIGN: A retrospective study of cases of proven ruptured IAs which were hospitalized during the 1973 to 1992 period was conducted. Age-adjusted rates were computed and compared to those reported in the Helsinki population. RESULTS: We identified 412 cases of ruptured aneurysms. The age-adjusted incidence rate was 7.2/100,000/year (6.2 for men, 8.1 for women), which is similar to the incidence rates reported in other studies. Although the mean age at time of rupture was younger (46.6 years +/- 13.8) than usually reported, no increase in age-specific incidence rates was detected. CONCLUSIONS: The results of this epidemiological study neither support nor reject the hypothesis of a genetic predisposition to intracranial aneurysms in the Saguenay-Lac-Saint-Jean population.
J Mathieu; L Pérusse; P Allard; C Prévost; L Cantin; J M Bouchard; M DeBraekeleer
Related Documents :
978239 - Angiographic study of the growth of intracranial aneurysms.
3218449 - Clinical brain death with preserved cerebral arterial circulation.
21543089 - Ischemic dose-response in the spinal cord: both immediate and delayed paraplegia.
20663399 - The accuracy and usefulness of 3d-dsa and 3d-ct angiography for cerebral aneurysms.
1633479 - Infectious intracranial aneurysms.
207089 - Effect of cardiac arrest on cerebral circulation. an experimental investigation.
15875609 - Heart failure due to giant congenital aorto-right atrial fistula: report of a case.
2949839 - Percutaneous transluminal recanalization of common iliac artery occlusions.
15216109 - Eversion endarterectomy: a new application of an old technique.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques     Volume:  23     ISSN:  0317-1671     ISO Abbreviation:  Can J Neurol Sci     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1997-01-06     Completed Date:  1997-01-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0415227     Medline TA:  Can J Neurol Sci     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  184-8     Citation Subset:  IM    
Unité de recherche clinique, Hôpital de Chicoutimi, Québec, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Age Factors
Aneurysm, Ruptured / epidemiology*
Child, Preschool
Infant, Newborn
Intracranial Aneurysm / epidemiology*
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The efficacy of retrograde infusion with LY231617 in a rat middle cerebral artery occlusion model.
Next Document:  Risk factors for peak dose dyskinesia in 100 levodopa-treated parkinsonian patients.