Document Detail

Epidemiological study design and the advancement of equine health.
MedLine Citation:
PMID:  19165940     Owner:  NLM     Status:  MEDLINE    
The primary purposes of epidemiological investigations are to learn about causal mechanisms related to disease incidence and identify factors for therapy and prevention. Epidemiological studies can be observational--further categorised as descriptive or analytical--or experimental. Investigators performing experimental studies, or randomised controlled trials (RCTs), randomly assign treatments or exposures to study participants for the expressed purpose of the study. The most frequently encountered observational epidemiological studies employed to investigate issues of equine health are cohort, case-control, cross-sectional and case series. A cohort study is an investigation in which the researcher follows (observes) a group, termed the cohort, over time to measure incidence of a particular outcome. A case-control study is an investigation in which the researcher selects a group of affected individuals (cases) and a comparison group (controls) to investigate factors associated with being a case. A cross-sectional study investigates a group of individuals for study that is often defined by membership in a target population and data concerning outcome and exposure are either collected related to the same time-point or data are collected by investigators at the same time. Case series are descriptive studies used to generate hypotheses concerning predictors of disease or recovery that can be performed retrospectively or prospectively. The best evidence for clinical practice is often derived from patient-centred observational epidemiological studies and it is imperative that equine veterinarians become familiar with study designs for the appropriate interpretation of epidemiological findings.
G T Fosgate; N D Cohent
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Equine veterinary journal     Volume:  40     ISSN:  0425-1644     ISO Abbreviation:  Equine Vet. J.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2009-01-23     Completed Date:  2009-02-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173320     Medline TA:  Equine Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  693-700     Citation Subset:  IM    
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A & M University, College Station, Texas, USA.
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MeSH Terms
Case-Control Studies
Cohort Studies
Cross-Sectional Studies
Epidemiologic Methods / veterinary*
Epidemiologic Research Design / veterinary*
Horse Diseases / epidemiology*
Randomized Controlled Trials as Topic / veterinary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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