| Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study. | |
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MedLine Citation:
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PMID: 14750619 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To study the epidemiological characteristics and laboratory diagnosis of fungal keratitis seen at a tertiary eye care referral centre in South India. METHODS: A retrospective review of all culture-proven fungal keratitis seen over a 3-year period, September 1999 through August 2002. RESULTS: Fungal aetiology were confirmed in 1095 (34.4%) of 3183 corneal ulcers. The predominant fungal species isolated was Fusarium spp (471; 42.82%) followed by Aspergillus spp (286; 26%). Males (712; 65.08%) were more often affected (P<0.0001). A large proportion of the patients (732; 66.85%) were in the younger age group (21 to 50 years). A majority (879; 80.27%) came from rural areas (P<0.0001), and most patients (709; 64.75%) were farmers (P<0.0001). Ocular trauma (1009; 92.15%) was a highly significant risk factor (P<0.0001) and vegetative injuries (671; 61.28%) were identified as a significant cause for fungal keratitis (P<0.0001). 172 (15.71%) patients had concurrent diabetes mellitus. The sensitivity of 10% potassium hydroxide (KOH) wet mount preparation was higher (99.23%) than Gram-stained smear (88.73%) (P<0.0001). Incidence of fungal keratitis was higher between June and September. CONCLUSION: Agricultural activity and related ocular trauma were principal causes of mycotic keratitis. A potassium hydroxide (KOH) wet mount preparation is a simple, and sensitive, method for diagnosis |
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Authors:
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M Jayahar Bharathi; R Ramakrishnan; Samala Vasu; R Meenakshi; R Palaniappan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of ophthalmology Volume: 51 ISSN: 0301-4738 ISO Abbreviation: Indian J Ophthalmol Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2004-01-30 Completed Date: 2004-04-16 Revised Date: 2008-09-03 |
Medline Journal Info:
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Nlm Unique ID: 0405376 Medline TA: Indian J Ophthalmol Country: India |
Other Details:
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Languages: eng Pagination: 315-21 Citation Subset: IM |
Affiliation:
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Department of Microbiology, Aravind Eye Care System, Tirunelveli, Tamil Nadu, India. aravind@tvl.aravind.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Diagnostic Techniques, Ophthalmological Eye Infections, Fungal / diagnosis, epidemiology*, microbiology Female Fungi / isolation & purification Humans India / epidemiology Keratitis / diagnosis, epidemiology*, microbiology Laboratory Techniques and Procedures Male Middle Aged Mycoses / diagnosis, epidemiology*, microbiology Referral and Consultation / statistics & numerical data Retrospective Studies Risk Factors Rural Population / statistics & numerical data Urban Population / statistics & numerical data |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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