Document Detail


Epidemiological and Clinical Data of Amniotic Fluid Embolism in Forensic Settings.
MedLine Citation:
PMID:  24804727     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Amniotic fluid embolism (AFE) is a serious obstetric emergency, burdened with a high rate of mortality and morbidity and possible permanent neurological sequelae for those women who survive. The clinical presentation commonly includes: acute hypotension or cardiac arrest, acute hypoxia (dyspnea, cyanosis or respiratory arrest) and coagulopathy (intravascular coagulation or severe haemorrhage), which usually occur during labour, caesarean section or within 30 minutes of delivery. Some cases for the rapidity of clinical presentation, which can result in fatal outcome, run the risk of not being recognized, therefore is fundamental in case of maternal death a proper post mortem examination and histological investigation in order to make the diagnosis and do not underestimate the incidence of this serious pathological condition. In this paper the Authors investigated the fatality rates in AFE patients and its incidence in pregnancy related deaths, extrapolating epidemiological data regarding the role of this pathology among the leading causes of maternal mortality. Secondly it has been evaluated the contribute of autopsy and further investigation performed post mortem in order to confirm or make the AFE diagnosis to better understand this clinical entity that still remain unclear under numerous aspects.
Authors:
Busardo Francesco Paolo; Frati Paola; B Steven Karch; Fineschi Vittorio
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-30
Journal Detail:
Title:  Current pharmaceutical biotechnology     Volume:  -     ISSN:  1873-4316     ISO Abbreviation:  Curr Pharm Biotechnol     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-5-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100960530     Medline TA:  Curr Pharm Biotechnol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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