Document Detail


Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data.
MedLine Citation:
PMID:  20440918     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND AIM: The relative frequency of histological subtypes of lung cancer in Europe has changed dramatically during the 20th century. The aim of this study was to explore the changing epidemiology of lung cancer in Northern Greece over the last two decades. METHODS: From the extensive database of the Bronchoscopy Unit of the G. Papanicolaou General Hospital, Thessaloniki, Greece, we identified all patients with a histologic and/or cytologic report positive for lung cancer over two consecutive decades. RESULTS: Between 1/1/1986 and 31/12/2005 we identified 9981 patients with specimens positive for lung cancer. A significant increase in mean patient age was observed during the second decade (64.8 +/- 9.4 vs. 62.1 +/- 8.9, p=0.001). Men developed lung cancer ten times more often than women. The predominant histological type was squamous cell cancer in males (4203 cases, 45.7%) and adenocarcinoma (418 cases, 52.6%) in females. The number of lung cancer cases was significantly higher during the second decade compared to the first decade (5766 cases [57.8%] vs. 4215 cases [42.2%], respectively, p<0.001). There was a significant decrease in the percentage of squamous cell carcinoma in males in the second decade (2317 cases [44.1%] vs. 1886 cases [48.0%], p<0.001), and an increase in adenocarcinoma (1021 cases [19.4%] vs. 609 [11.6%], p<0.001). In females, the relative incidence of adenocarcinoma was decreased and that of squamous cell carcinoma was increased, but not significantly. There was no obvious change in the incidence of small cell lung cancer. Neoplastic lesions were most often located in the upper lobes. CONCLUSION: The number of lung cancer cases has increased in the last decade. Squamous lung cancer appears to be decreasing in men and increasing in women. Adenocarcinoma appears to be increasing in men and decreasing in women. There appears to be no change in small cell lung cancer. During the second decade there has been a significant decrease in the male: female ratio.
Authors:
T Kontakiotis; N Manolakoglou; F Zoglopitis; D Iakovidis; L Sacas; A Papagiannis; A Mandrali; D Papakosta; P Argyropoulou; D Bouros
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Universit? di Napoli, Secondo ateneo     Volume:  71     ISSN:  1122-0643     ISO Abbreviation:  Monaldi Arch Chest Dis     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-05-05     Completed Date:  2010-06-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9307314     Medline TA:  Monaldi Arch Chest Dis     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  147-52     Citation Subset:  IM    
Affiliation:
Bronchoscopy Unit, Dept. of Pneumonology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece. kontak@auth.gr
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MeSH Terms
Descriptor/Qualifier:
Adenosarcoma / epidemiology*
Adult
Age Distribution
Aged
Bronchoscopy*
Databases, Factual
Female
Greece / epidemiology
Humans
Lung Neoplasms / epidemiology*,  pathology*
Male
Middle Aged
Neoplasms, Squamous Cell / epidemiology*
Prevalence
Sex Distribution
Small Cell Lung Carcinoma / epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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